Levofloxacin-induced Fatal Hypoglycaemia in a Non-diabetic Patient: A Case Report
Published: September 1, 2023 | DOI: https://doi.org/10.7860/JCDR/2023/62537.18424
Yash N Panchal, Bhavesh M Vyas
1. Third Year Postgraduate Resident, Department of Pharmacology, AMC MET Medical College, Ahmedabad, Gujarat, India.
2. Associate Professor, Department of Pharmacology, AMC MET Medical College, Ahmedabad, Gujarat, India.
Correspondence
Dr. Yash N Panchal,
Associate Professor, Department of Pharmacology, AMC MET Medical College, Maninagar, Ahmedabad-380028, Gujarat, India.
E-mail: dryashpanchal95@gmail.com
Levofloxacin, a broad-spectrum, third-generation fluoroquinolone antibiotic, is rarely reported to cause life-threatening adverse effects, such as severe hypoglycaemia resulting in a coma. This case concerns hypoglycaemia in an elderly, non-diabetic patient induced by levofloxacin. A 61-year-old male patient was admitted with severe hypoglycaemia. Past medical history revealed treatment with levofloxacin for pneumonia. During the hospital stay, the patient was treated with multiple doses of 25 g dextrose 50% (D50), 2 doses of 1 mg glucagon, and a continuous infusion of dextrose 10% (D10). The patient was discharged on the sixth day of admission in a stable condition with no clinical symptoms. Clinicians must be aware of this lesser-known adverse effect to ensure quick recognition and treatment with the proper adjuncts.
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